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American ginseng (Panax quinquefolius)

Araliaceae · root

American ginseng

Panax quinquefolius

Human clinical trialsUse with caution

North American Panax mapped to human glycemic and upper-respiratory trial literature of specified extracts. Cooler/more yin in TCM terms than P. ginseng — still not a candy.

Safety first

Root has human data for postprandial glucose and some cold-season endpoints. Bleeding and hypoglycemia cautions still apply. Wild populations are conservation-sensitive.

Tradition vs trials

Traditional record. Used in North American herbalism and adopted into TCM as xiyangshen, generally cooler than ren shen.

Trial literature. Human trials of specified root extracts report postprandial glucose changes and some cold-season symptom or incidence endpoints. Products are not interchangeable.

Practical ranges

Educational ranges — not a prescription. Culinary use is not an extract.

  • root extract

    Glycemic and cold-season trials often use a few hundred milligrams to a few grams of specified extract daily; crude-root traditional amounts differ

    NCCIHEducational range only — not a prescription. A licensed clinician individualizes product, dose, and duration.

Pregnancy, nursing, children

  • Pregnancy. Insufficient reliable data; avoid unless a clinician directs otherwise.
  • Nursing. Insufficient reliable data; avoid unless a clinician directs otherwise.
  • Children. Insufficient reliable data; avoid unless a clinician directs otherwise.

Contraindications

  • unsupervised use with insulin or sulfonylureas
  • known Panax allergy

Key interactions

  • antidiabetes drugs · caution

    Additive hypoglycemia possible.

  • anticoagulants / antiplatelets · caution

    Class bleeding caution shared with Panax.

Open drug–herb checker

Used in these diagnoses