Skip to content
Rooted

Endocrine / Metabolic

Fatigue related to metabolic issues

3 plants

Ask Assistant about this

If A1c, ferritin, TSH, and PHQ-9 are untouched, adaptogens are theater.

Primary plants

  1. Ashwagandha (Withania somnifera)
    1
    AshwagandhaHuman data

    Withania somnifera

    Fatigue/stress RCTs.

    Typical. Extract 300–600 mg.

    Safety. Pregnancy, thyroid, DILI.

  2. Asian ginseng (Panax ginseng)
    2
    Asian ginsengHuman data

    Panax ginseng

    Fatigue traditional + mixed trials. Can worsen insomnia/HTN.

    Typical. Root extract 200–400 mg.

    Safety. Insomnia, INR, HTN.

Supportive plants1
  • American ginseng (Panax quinquefolius)
    American ginsengHuman data
    Panax quinquefolius

    Some post-prandial glucose and fatigue data. Milder stimulant than Panax.

    Typical. Root 1–3 g or extract as studied.

    Safety. INR (American ginseng can drop warfarin INR).

When this is not enough

  • Unexplained weight loss, night sweats, syncope, severe anemia, SI

Rooted is a private clinical reference for licensed practitioners. It is educational, not a treatment protocol, and not a substitute for the chart, the exam, or pharmacy review. Plant medicines interact with drugs and can harm liver, kidney, heart, pregnancy, and children.

All endocrine / metabolic diagnoses