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Rooted

Hepatic

Alcohol-associated liver disease (warning)

4 plants

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This page is a stop sign. Milk thistle (silymarin) has a long hepatology folklore file and mixed modern data — it does not reverse cirrhosis or license continued drinking. Kava has a DILI file of its own. Internal comfrey is a PA-alkaline hard no. High-dose curcumin/piperine is another DILI object. Acetaminophen plus alcohol plus a 'liver cleanse' is a classic own-goal.

Primary plants

  1. Milk thistle (Silybum marianum)
    1
    Milk thistleHuman data

    Silybum marianum

    Silymarin: long hepatology tradition, mixed modern outcome data. Not an antidote and not permission to keep drinking.

    Typical. Seed extract as labeled if they already take it — counsel that abstinence is the intervention.

    Safety. GI. Not a substitute for alcohol cessation or transplant referral.

  2. Kava (Piper methysticum)
    2
    KavaHuman data

    Piper methysticum

    Anxiolytic with a hepatotoxicity file. The wrong plant on this page.

    Typical. Do not use.

    Safety. DILI. Alcohol stacking. Hard no here.

  3. Comfrey (Symphytum officinale)
    3
    ComfreyStrong traditional

    Symphytum officinale

    PA alkaloids. Veno-occlusive disease. Never internal.

    Typical. Do not use internally. Topical is a different, still-cautious object.

    Safety. Hepatic VOD. Hard no internally.

Supportive plants1
  • Turmeric (Curcuma longa)
    TurmericHuman data
    Curcuma longa

    Culinary is food. Extract is a documented DILI object — especially with piperine.

    Typical. Food only on this page.

    Safety. DILI. Bleed.

Clinical notes

  • Jaundice, ascites, or a rising INR is hepatology, not a higher silymarin dose.

When this is not enough

  • Acute liver failure, encephalopathy, GI bleed, withdrawal seizures, acetaminophen co-ingestion

Rooted is a private clinical reference for licensed practitioners. It is educational, not a treatment protocol, and not a substitute for the chart, the exam, or pharmacy review. Plant medicines interact with drugs and can harm liver, kidney, heart, pregnancy, and children.

All hepatic diagnoses