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Yohimbe (Pausinystalia johimbe)

Rubiaceae · bark

Yohimbe

Pausinystalia johimbe

Human clinical trialsRestricted / professional onlyToxicity warning

Bark mapped as a toxicity-leaning restricted entry because marketing still sells it for libido and fat loss. NCCIH-class summaries do not support unsupervised use.

Safety first

Yohimbine is an alpha-2 antagonist: hypertension, tachycardia, anxiety, priapism reports. MAOI and stimulant stacking is dangerous. Not a gym supplement. Restricted / professional-adjacent; dietary products are poorly assayed.

This entry exists so you do not use the plant casually. It is not a treatment suggestion.

Tradition vs trials

Traditional record. West African bark that became a 20th-century Western drug/supplement object. Traditional use is not a safety file.

Trial literature. Yohimbine has human autonomic and some erectile-dysfunction pharmacology. Adverse-event reports dominate the educational story.

Practical ranges

Educational ranges — not a prescription. Culinary use is not an extract.

  • bark / yohimbine

    No unsupervised range in this catalog

    NCCIH / FDA-era supplement warningsEducational range only — not a prescription. A licensed clinician individualizes product, dose, and duration.

Pregnancy, nursing, children

  • Pregnancy. Avoid.
  • Nursing. Avoid.
  • Children. Avoid.

Contraindications

  • uncontrolled hypertension
  • panic disorder
  • unsupervised sexual-enhancement use

Key interactions

  • MAOIs / decongestants / stimulants / antidepressants · contraindicated

    Pressor and psychiatric stacking.

Open drug–herb checker

Used in these diagnoses