Genitourinary · also Cardiovascular
Erectile dysfunction (adjunct / warning)
4 plants
Ask Assistant about thisED is a cardiovascular risk marker until you look. PDE5 inhibitors have the outcome file; nitrates are the hard interaction. Yohimbe (alpha-2 antagonist) is in the catalog as a warning — HTN, arrhythmia, panic. Asian ginseng has some mixed ED trial data and insomnia/INR costs. Ginkgo is a bleed next to a future angiogram. This is not a reason to skip a lipid panel.
Primary plants
1Asian ginsengHuman dataPanax ginseng
Some mixed human ED/sexual-function data. Insomnia, BP, INR. Not a PDE5.
Typical. Root extract 200–400 mg if they insist on a plant after the CV screen.
Safety. Insomnia, HTN, warfarin INR. Not nitrates+PDE5 counseling.
2YohimbeStrong traditionalPausinystalia johimbe
Alpha-2 antagonist toxicity object. HTN, tachycardia, panic, seizure. Not a bedroom supplement.
Typical. Do not use.
Safety. Pressor crises, arrhythmia. Hard no.
Supportive plants2
GinkgoHuman dataGinkgo bilobaCirculation marketing. Bleed. Mixed sexual-function data.
Typical. Usually skip next to antiplatelets.
Safety. Bleed.
Velvet beanStrong traditionalMucuna pruriensMucuna: L-dopa-containing. A Parkinson's-adjacent object, not an ED drug. Nausea, add-on to levodopa is a specialist problem.
Typical. Do not start it for ED.
Safety. Nausea. Dopaminergic stacking.
Clinical notes
- Chest pain on a PDE5, or a nitrate in the med list, is the interaction that matters — not ginseng.
When this is not enough
- Unstable angina, nitrate use, priapism, sudden vision/hearing loss on a PDE5
Rooted is a private clinical reference for licensed practitioners. It is educational, not a treatment protocol, and not a substitute for the chart, the exam, or pharmacy review. Plant medicines interact with drugs and can harm liver, kidney, heart, pregnancy, and children.