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Senna (Senna alexandrina)

Fabaceae · leaflet, fruit (pod)

Senna

Senna alexandrina

Human clinical trialsRestricted / professional only

Leaf and pod are mapped to well-documented stimulant-laxative pharmacology and short-term human use. European monographs strictly limit duration.

Safety first

Short-term stimulant laxative only. Chronic use risks electrolyte loss, dependence, and melanosis coli. Not a daily 'cleanse' and not for unexplained abdominal pain.

Tradition vs trials

Traditional record. Alexandrian and Tinnevelly senna have a long purgative record in Western, Unani, and Ayurvedic pharmacy.

Trial literature. Human bowel-prep and constipation trials confirm a stimulant effect. That is not evidence for chronic wellness use.

Practical ranges

Educational ranges — not a prescription. Culinary use is not an extract.

  • sennosides (adults, short-term)

    European monographs typically list about 15–30 mg hydroxyanthracene glycosides (as sennoside B) at bedtime, generally not beyond 1–2 weeks

    EMA HMPC / German Commission EEducational range only — not a prescription. A licensed clinician individualizes product, dose, and duration.

Pregnancy, nursing, children

  • Pregnancy. Avoid unless a clinician directs a short-term stimulant laxative. Osmotic or bulk options are usually considered first.
  • Nursing. Anthraquinones can appear in milk; European monographs advise against routine nursing use unless a clinician directs otherwise.
  • Children. Not for children unless a clinician directs a specific product and duration. Infants are excluded.

Contraindications

  • ileus or bowel obstruction
  • acute inflammatory bowel disease flares
  • undiagnosed abdominal pain
  • severe dehydration
  • chronic daily self-use

Key interactions

  • diuretics / digoxin / corticosteroids · avoid

    Potassium loss potentiates arrhythmia and digoxin toxicity.

Open drug–herb checker

Used in these diagnoses