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King of bitters (Andrographis paniculata)

Acanthaceae · aerial parts

King of bitters

Andrographis paniculata

Human clinical trialsUse with caution

Mapped to human common-cold duration trials of standardized andrographolide products. Culinary or folk decoctions are not those products.

Safety first

Bitter aerial parts have cold-duration trial literature. Pregnancy avoid. Taste is frankly bitter. Not a flu antiviral of record. Autoimmune/transplant caution is theoretical but listed.

Tradition vs trials

Traditional record. Ayurvedic and SE Asian bitter febrifuge (kalmegh). Later European common-cold products.

Trial literature. Human URI-duration trials exist; quality and products vary. Not a substitute for influenza or COVID evaluation in high-risk hosts.

Practical ranges

Educational ranges — not a prescription. Culinary use is not an extract.

  • standardized aerial extract (adults)

    Cold-duration products in European/Asian trials often provide tens of milligrams of andrographolide daily for a few days — product-specific, not a prescription

    ESCOP / EMA HMPC / trial literature summariesEducational range only — not a prescription. A licensed clinician individualizes product, dose, and duration.

Pregnancy, nursing, children

  • Pregnancy. Avoid.
  • Nursing. Insufficient reliable data; avoid unless a clinician directs otherwise.
  • Children. Not a pediatric DIY febrifuge.

Contraindications

  • pregnancy
  • do not delay evaluation of pneumonia, epiglottitis, or sepsis

Key interactions

  • immunosuppressants · caution

    Theoretical immune modulation. Transplant drugs need a clinician, not a bitter.

Open drug–herb checker

Used in these diagnoses