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Hepatic · also Digestive, Endocrine / Metabolic

NAFLD / metabolic liver fat

Plants are adjunctive at best. Milk thistle (silymarin) has a mixed human file and is not a substitute for weight change, alcohol history, and diabetes care. Green-tea extract is a liver-injury risk — do not stack it here.

Primary plants

  1. Milk thistle (Silybum marianum)
    1
    Milk thistleHuman data

    Silybum marianum

    Silymarin has mixed human data in liver-enzyme and some NAFLD-adjacent trials. Adjunct only.

    Typical. Seed extract, often 140 mg silymarin tid — product-variable.

    Safety. Generally well tolerated. CYP interactions theoretical. Quality/silybin content varies.

  2. Artichoke (Cynara scolymus)
    2
    ArtichokeStrong traditional

    Cynara scolymus

    Bitter/choleretic for dyspepsia with a metabolic-adjacent tradition. Not a NASH reversal plant.

    Typical. Leaf extract as on the dyspepsia page.

    Safety. Bile-duct obstruction.

Supportive plants1
  • Turmeric (Curcuma longa)
    TurmericHuman data
    Curcuma longa

    Metabolic-inflammation extract file. Rare DILI — ironic on a liver page.

    Typical. Food spice safer than high-dose curcuminoids here.

    Safety. Stop for jaundice. Piperine interactions.

Clinical notes

  • Do not add kava, comfrey, or high-dose GTE to a fatty-liver chart.

When this is not enough

  • Jaundice, decompensated cirrhosis, acute hepatitis, unexplained ALT >3–5×

Rooted is a private clinical reference for licensed practitioners. It is educational, not a treatment protocol, and not a substitute for the chart, the exam, or pharmacy review. Plant medicines interact with drugs and can harm liver, kidney, heart, pregnancy, and children.

All hepatic diagnoses