Nervous / Mental
Migraine prevention
4 plants
Ask Assistant about thisThis is prevention, not the triptan/gepant/ditans for the attack. Feverfew has a mixed prevention file and mouth-ulcer/rebound issues. Butterbur (Petasites) has human migraine-prevention data — only certified PA-free extracts; raw herb is hepatotoxic. Magnesium and sleep still matter. Thunderclap is SAH until proven otherwise.
Primary plants
1FeverfewHuman dataTanacetum parthenium
Leaf: human migraine-prevention file, mixed quality. Not acute abortive.
Typical. Leaf 50–150 mg/day for prophylaxis, not the attack.
Safety. Mouth ulcers, rebound if stopped, Asteraceae, anticoagulants.
2ButterburHuman dataPetasites hybridus
PA-free Petasites has human migraine-prevention trials. Raw herb is hepatotoxic.
Typical. Certified PA-free extract as labeled (product-specific petasin dose).
Safety. Only certified PA-free. Avoid in liver disease and pregnancy. Asteraceae allergy.
Supportive plants2
PeppermintHuman dataMentha × piperita10% peppermint oil topical is a TTH/attack-comfort file more than prevention.
Typical. Topical to temples for an attack adjunct. Keep off eyes.
Safety. Irritation. Not for infants.
GingerHuman dataZingiber officinaleSome people use it at onset for the nausea arm of migraine.
Typical. 1–2 g dried at onset.
Safety. Extracts: bleeding.
When this is not enough
- Thunderclap, focal neuro, fever with stiff neck, new migraine after 50, pregnancy migraine decisions without OB
Rooted is a private clinical reference for licensed practitioners. It is educational, not a treatment protocol, and not a substitute for the chart, the exam, or pharmacy review. Plant medicines interact with drugs and can harm liver, kidney, heart, pregnancy, and children.