Burseraceae · oleo-gum-resin
Guggul
Commiphora wightii
Classical scraping/kapha-metabolic resin and the chief of guggulu yogas such as Kaishore Guggulu. Human lipid data conflict.
Safety first
Resin with conflicting lipid-trial literature and thyroid-test signals. Drug-interaction potential (including thyroid and some CYP stories) is a clinician problem. Conservation: wild C. wightii is pressured. Not a statin.
Tradition vs trials
Traditional record. Ayurvedic Pharmacopoeia: guggulu resin in lekhana and joint-metabolic yogas.
Trial literature. Guggulsterone extracts have human lipid trials that conflict (including a well-known negative US trial). NCCIH-class summaries do not treat this as lipid-guideline care.
Practical ranges
Educational ranges — not a prescription. Culinary use is not an extract.
resin / extract
Trial extracts often in the low-gram resin or standardized-guggulsterone range — product-specific, conflicting outcomes, not a prescription
NCCIH / Ayurvedic Pharmacopoeia of India — Educational range only — not a prescription. A licensed clinician individualizes product, dose, and duration.
Pregnancy, nursing, children
- Pregnancy. Avoid.
- Nursing. Insufficient reliable data; avoid unless a clinician directs otherwise.
- Children. Insufficient reliable data; avoid unless a clinician directs otherwise.
Contraindications
- pregnancy
- as a statin replacement
- unsupervised thyroid self-treatment
Key interactions
- thyroid hormones / some CYP substrates · caution
Thyroid-test signals and interaction lists exist. A pharmacist reviews the actual list.