Menispermaceae · stem
Guduchi
Tinospora cordifolia
Stem mapped as a classical bitter rasayana with a modern product-hepatotoxicity file that must sit in front.
Safety first
Classical pitta-supporting rasayana. Some Tinospora products (including T. crispa and labeled T. cordifolia) have been tied to liver-injury clusters. Species identity is a safety issue, not a footnote.
Tradition vs trials
Traditional record. Ayurvedic Pharmacopoeia: guduchi stem as rasayana, jvarahara, and pitta-kapha language.
Trial literature. Human files are mixed and product-specific. CDC/FDA-era liver-injury reports with Tinospora-containing products are the safety literature.
Practical ranges
Educational ranges — not a prescription. Culinary use is not an extract.
stem
Classical ranges in API; not a prescription, and product liver-injury reports override casual use
Ayurvedic Pharmacopoeia of India — Educational range only — not a prescription. A licensed clinician individualizes product, dose, and duration.
Pregnancy, nursing, children
- Pregnancy. Avoid unsupervised.
- Nursing. Insufficient reliable data; avoid unless a clinician directs otherwise.
- Children. Insufficient reliable data; avoid unless a clinician directs otherwise.
Contraindications
- pre-existing liver disease without a clinician
- unidentified 'giloy' products
Key interactions
- hepatotoxic drugs · avoid
Product-level liver injury reports. Do not stack.